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Tests for Female Partner

Those who are about to undergo fertility treatment for the first time

beginner = these tests will be conducted.

Those who have already completed tests at other clinic.

The tests numbered12345must be done.

Others will be discussed and implemented upon request or when the doctor deems it necessary.

  • The blood test
  • X-ray test
  • Ultrasound test
  • Initial Infertility Test

Menstrual phase

D1~D5

1FSH blood sampling test

beginnerThis test is performed on days 1-5 of your period.

2LH blood sampling test

beginnerThis test is performed on days 1-5 of your period.

3Prolactin hormone blood sampling test

beginnerThis test is performed on days 1-5 of your period.

Follicular phase

D6~D12

8Hysterosalpingography

beginnerThis test is performed on days 6-12 of your period.

9Hysteroscopy

beginnerThis test is performed on days 6-12 of your period.

4Estrogen blood sampling test

beginnerThis test is performed on days 6-12 of your period.

6The Ultrasound test

beginnerThis test is performed on days 10-12 of your period.

Ovulation phase

D13~D15

7Huhner test

beginnerThis test is performed on days 10-12 of your period.

Luteal phase

D16~D28

10ERA EMMA ALICE

beginnerThis test is performed on days 19-24 of your period.

6The Ultrasound test

beginnerThis test is performed on days 19-24 of your period.

4Estrogen blood sampling test

beginnerThis test is performed on days 19-24 of your period.

5Progesterone blood sampling

beginnerThis test is performed on days 19-24 of your period.

1FSH blood sampling testbeginner

A hormone secreted by the pituitary gland that stimulates the ovaries to secrete estrogen and promote the maturation of follicles.

  • Standard Level5~8mIU/ml
  • Health insurance¥330
  • Actual cost¥2,420(Tax included)

2LH blood sampling testbeginner

It is secreted by the pituitary gland and induces the onset of ovulation through rapid secretion. It is also promotes the formation of the corpus luteum after ovulation.

  • Standard Level2~5miu/ml LH surge40~60mIU/ml
  • Health insurance
  • Actual cost¥2,420(Tax included)

3Prolactin hormone blood sampling testbeginner

This hormone is secreted by the pituitary gland, and as its other name - milk secreting hormone - suggests, it is secreted in large amounts by postpartum mothers. Both men and women secrete small amounts of this hormone even in normal conditions, but high levels can cause infertility in both men and women. In particular, subclinical hyperprolactinemia is a problem in infertility.

  • Standard LevelLess than 35ng/ml
  • Health insurance
  • Actual cost¥2,035(Tax included)

4Estrogen blood sampling test beginner

It is secreted by the granulosa cells of the ovaries and thickens the endometrium during the follicular phase and increases the amount of cervical mucus before ovulation.

  • Standard LevelMore than 200-250 pg/ml before ovulation
  • Health insurance¥530
  • Actual cost¥2,420(Tax included)

5Progesterone blood sampling beginner

Progesterone is a hormone secreted by the corpus luteum, which is formed after ovulation, and it raises the basal body temperature and acts on the endometrium to create an environment where the embryo can implant easily through endometrial growth.

  • Standard LevelMore than 10 pg/ml on days 19-24 of menstruation
  • Health insurance¥450
  • Actual cost¥2,420(Tax included)

6Ultrasound Test beginner

An ultrasound is performed with a transvaginal probe. It also measures follicles before ovulation, endometrial thickness, ovarian swelling, and fibroids.

  • Standard LevelFollicle diameter of 16 mm around the 10th day of menstruation
  • Health insurance
  • Actual cost¥2,200(Tax included)

7Huhner test

The test is performed by having intercourse early in the morning on the day of ovulation or late in the evening of the night before to check the penetration of sperm into the cervix. The test can be done up to 12 hours after intercourse.

  • Standard Level
  • Health insurance
  • Actual cost¥4,710(Tax included)

8Hysterosalpingography beginner

Hysterosalpingogram is a test to examine the passage of the fallopian tubes, adhesions of the fallopian tubes, and the condition of the uterine cavity.

  • Standard Level
  • Health insurance
  • Actual cost¥8,360(Tax included)

9Hysteroscopy beginner

An endoscope is inserted through the uterine opening to directly observe the inner surface of the uterus to check for abnormalities in the endometrium.

  • Standard Level
  • Health insurance¥2,400
  • Actual cost¥19,800(Tax included)

10ERA EMMA ALICE beginner

ERA is a test to determine the implantation receptive period of an individual, and at the same time, a test to determine the percentage of lactobacilli suitable for implantation in the uterus (EMMA), and a test to determine the presence of bacteria that cause chronic endometritis (ALICE), which can lead to sterility and infertility.

  • Standard Level
  • Health insurance
  • Actual cost¥71,500~198,000(Tax included)

11Thyroid function test(TSH、FT4) beginner

Thyroid hormones are responsible for regulating hormone action and balance. They can be either overactive or underactive, both of which can affect fertility and cause infertility.

  • Standard Level
  • Health insurance
  • Actual cost¥4,202(Tax included)

12Tests for Infectious disease(HBs antigen, HCV antibody, RPR, TP antibody, rubella HI antibody, Chlamydia PCR, HIV, HTLV-1 antibody(PA)) beginner

This is a preliminary test for infections that may affect both mother and child in future pregnancies.

  • Standard Level
  • Health insurance
  • Actual cost¥11,198(Tax included)

13Anti-müllerian hormone test(AMH) beginner

Since AMH is secreted by developing follicles and pre-follicular follicles, its value correlates with developing follicles. Since AMH levels decrease with age in adult women, it is a good indicator of ovarian reserve function. It is also high in PCO.

  • Standard LevelReference values vary according to age.
  • Health insurance
  • Actual cost¥7,700(Tax included)

14Testosterone test

When testosterone levels are high, menstrual abnormalities, ovulation disorders, etc. are suspected. It is especially high in PCO and is used in combination with ultrasound findings for diagnosis.

  • Standard Level0.2~0.8ng/ml
  • Health insurance
  • Actual cost¥2,112(Tax included)

15Primary screening for implantation failure and infertility (Antiphospholipid antibody test, antinuclear antibody test, antisperm antibody test, thyroid function test, coagulation test)

Because implantation is the result of a complex interplay of cellular correlations between the embryo and the endometrium under the influence of hormones, the entire implantation process is re-examined. After re-examining endocrine abnormalities, the condition of the endometrium, implantation regulating factors, and the condition of the embryo (fertilized egg, abnormalities in the clear zone), a hysteroscopy is performed.

  • Standard Level
  • Health insurance
  • Actual cost¥28,600(Tax included)

16Chromosome test (before 2pm on weekdays)

Chromosome testing is performed in cases of habitual miscarriage, severe sperm reduction, and azoospermia. Chromosomal abnormalities are found in 7% of men with severe sperm reduction and 18% of men with azoospermia.

  • Standard LevelMale 46XY, Female 46XX
  • Health insurance¥7,890
  • Actual cost¥33,000(Tax included)

17CA125

It is elevated in Ovarian cyst, endometriosis and ovarian cancer.
The test is used as an indicator of the activity of endometriosis.

  • Standard Level35u/ml以下
  • Health insurance¥430
  • Actual cost¥1,440(Tax included)

18Antisperm antibodies(Not required if (10) is completed.)

Normal women do not have this condition, but if antibodies to sperm are produced due to a breakdown in the immune system, it can interfere with fertilization and division, and even cause habitual miscarriage. Frequent insemination is the most common cause. In male partner, genital injuries due to car accidents and other causes can also be the cause.

  • Standard LevelNegative
  • Health insurance
  • Actual cost¥10.261(Tax included)

19Antinuclear antibodies(Not required if (10) is completed.)

An autoimmune antibody that appears in cases of unexplained repeated miscarriage or implantation failure. If the patient is positive for antibodies, she should be treated according to the treatment for infertility.

  • Standard LevelLess than 40 times
  • Health insurance
  • Actual cost¥1,251(Tax included)

20MRI

MRI is performed when intra-abdominal disease, uterine fibroids, or ovarian tumors are suspected. A painless and detailed test is possible.

  • Standard Level
  • Health insurance
  • Actual costDepends on the number of films

Tests for Male Partner

  • The blood test
  • X-ray test
  • Ultrasound test
  • Initial Infertility Test

ASemen analysis (computer analysis + normal sperm morphology rate) beginner

The Computerized Sperm Analysis System (CASA) uses computer analysis to perform detailed analysis of sperm motility, velocity, and straightness, and evaluates them in comparison to WHO standards. In addition, the normal sperm morphology rate is determined by applying a special stain to the sperm and then magnifying it 1000 times to check the head and tail.

  • Standard Level
  • Health insurance
  • Actual cost¥9,240(Tax included)

BSemen analysis + DFI test (computer analysis + sperm normal morphology rate + DNA damage rate)

In addition to the test in A, the DNA damage rate of the sperm (i.e., sperm quality) is examined.

  • Standard Level
  • Health insurance
  • Actual cost¥27,940(Tax included)

CMale Infertility Screening Set Test (Testosterone, AST, ALT, ALP, LDH, γ-GTP, Total Bilirubin, Direct Bilirubin, TP, ALB Quantification, Na, K, Cl, UN, Cre, Glu, Inorganic Phosphorus (IP), Calcium, Magnesium, Uric Acid, Serum Copper, Serum Iron, Total cholesterol, triglyceride, HDL-C, LDL-C, serum zinc, Chlamydia trachomatis real-time PCR, LH precision measurement, FSH precision measurement, PRL precision measurement, HIV I/II, HCV antibody, RPR, TP antibody, HTLV-1 antibody, HBs antigen)

A comprehensive test of male infertility such as sperm depletion and sperm aplasia is performed, along with a semen analysis.

  • Standard Level
  • Health insurance
  • Actual cost¥23,650(Tax included)

DChromosome test (before 2pm on weekdays)

In cases of severe sperm reduction and azoospermia, chromosome testing is performed. Chromosomal abnormalities are found in 7% of men with severe sperm reduction and 18% of men with azoospermia.

  • Standard Level46XY
  • Health insurance¥7,890
  • Actual cost¥33,000(Tax included)

EY chromosome microdeletion analysis (before 2pm on weekdays)

Y chromosome microdeletions are one of the causes of male infertility. The AZF (Azoospermia factor) region on the Y chromosome, which is said to play an important role in spermatogenesis, is examined for deletions and their locations. If there is a deletion of AZFc, there is a chance that sperm can be retrieved, but if there is a complete deletion of AZFa or AZFb, or a complete deletion of AZFb+c, there is no chance that sperm can be retrieved. Before TESE, we will determine if there is a chance of getting sperm.

  • Standard Level
  • Health insurance
  • Actual cost¥44,000(Tax included)
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